Abstract Clearance of protein waste products from the brain is accomplished by a combination of Cooktops advection and diffusion in cerebrospinal fluid (CSF) and interstitial fluid (ISF).In the glymphatic model, there is a flow of ISF in the interstitial space, and both advection and diffusion occur there.Such a flow of ISF would be slow and diffic

The main trends in bridge building are: the implementation of new materials, the assimilation of novel technologies, and the construction time reduction.The new technologies assimilation is often associated with the need to build bridge structures in cramped conditions.Considered by the author balanced lowering method technology corresponds to thes

Abstract Boredom has been defined as an aversive mental state that is induced by the disability to engage in satisfying activity, most often experienced in monotonous environments.However, current understanding of the situational factors inducing boredom and driving subsequent behavior remains incomplete.Here, we introduce a two-alternative forced-

Summary: Currently, patients receiving cancer treatments routinely suffer from distressing toxic effects, most originating from premature drug leakage, poor biocompatibility, and off-targeting.For tackling this challenge, we construct an intracellular Ca2+ cascade for tumor therapy via photothermal activation of TRPV1 channels.The nanoplatform crea